Manufacturing Platforms

Caliber has broad capabilities in plant, cell culture, and microbial-based expression systems. With these capabilities, Caliber maintains the full range of options for biological product development and manufacturing to respond to current unmet patient and global needs.

Plant-Made Pharmaceuticals

Caliber is a leader in the Plant-made (N. benthamiana) pharmaceuticals (PMP) production platform. This platform offers a number of advantages over traditional systems for the development and production of protein therapeutics such as monoclonal antibodies.

 

  • The flexibility and speed of plant technology enables high throughput screening and optimization of biotherapeutics before they ever reach clinical trials.
  • Plants are able to make novel and complex molecular forms that cannot otherwise be produced in cell-based systems, thus providing the opportunity to open new treatment paradigms for patients with unmet medical needs.
  • There are significantly lower facility and production costs associated with plant-based technology.
  • Plant-based systems are more likely to scale to meet increased and varied demand, from personalized to global applications.
  • The speed of production allows accelerated screening of new therapeutics and vaccines against emerging threats inclubing pandemic events.
  • Plant-based technology offers less risk of propagating human pathogens or other mammalian contaminants.